IL-5 protein
ORB107749
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameIL-5 protein
- Delivery Days Customer16
- Applications SupplierHPLC, SDS-PAGE
- CertificationResearch Use Only
- Scientific DescriptionRecombinant Rat Interleukin-5. IL-5, also named B-cell differentiation factor I, eosinophil differentiation factor and TRF, is belonging to the cytokine family and the IL-5 gene is in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunroglobulin secretion. It is also a key mediator in eosinophil activation. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.Rat IL-5 is a 132-amino acid (115 in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely IL-3 and GM-CSF), this glycoprotein in its active form is a homodimer.
- SourceE.coli
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202