Bio-Connect

IL15 Receptor alpha blocking peptide

Research Use Only
GTX31523-PEP
GeneTex
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL15 Receptor alpha blocking peptide
  • Delivery Days Customer
    10
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Concentration
    200 ug/ml
  • Scientific Description
    This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202