Golidocitinib [2091134-68-6]

MedChem Express

Golidocitinib [2091134-68-6]

10

2091134-68-6

98%

C25H31N9O2

489.57

Golidocitinib (AZD4205) is a selective JAK1 inhibitor, with an IC50 of 73 nM, weakly inhibits JAK2 (IC50>14.7 microM), and shows little inhibition on JAK3 (IC50>30 microM).

C[C@@H](N1CCN(C)CC1)C(NC2=C3C(C(C4=NC(NC5=CN(C)N=C5OC)=NC=C4)=CN3)=CC=C2)=O

2°C to 8°C,-20°C,-80°C

12352200