LAG-3 (human):Fc (human) (rec.)

Catalog number: CHI-HF-210LAG3-C050
Brand: Chimerigen Laboratories
Packing: 50 ug
Price: € 330.00
Expected delivery time: 7 days
Quantity:

Product specifications for - LAG-3 (human):Fc (human) (rec.)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Species: Human
Target: LAG3
Target description: lymphocyte activating 3
Source: 293 Cells
Properties: 
Purity: >98% (SDS-PAGE)
Molecular weight: ~95kDa (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Form supplied: Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions: -20-¦C
Scientific information: 
Scientific info: Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. - Protein. The extracellular domain of human LAG-3 (aa 29 - 450) is fused to the N-terminus of the Fc region of human IgG1. Source: HEK 293 cells. Endotoxin content: <5EU/mg purified protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS. Purity: >98% (SDS-PAGE). Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Gene ID: 3902
Swiss prot ID: P18627
Additional information: 
Synonyms: CD223; lymphocyte activation gene 3 protein; lymphocyte-activation gene 3; Protein FDC