Bio-Connect

Monkey EpCAM protein

Research Use Only
ORB257427
Biorbyt
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Monkey EpCAM protein
  • Delivery Days Customer
    16
  • Applications Supplier
    SDS-PAGE
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Scientific Description
    EpCAM is also known as CO171A, EGP, EGP40,GA7332, KSA, M4S, MIC18, MK1, TROP1, hEGP2, and is a pan-epithelial differentiation antigen that is expressed on almost all carcinomas as 17-1A(mAb) antigen. Its constitutional function is being elucidated. It is intricately linked with the Cadherin-Catenin pathway and hence the fundamental WNT pathway responsible for intracellular signaling and polarity. The epithelial cell adhesion molecule (Ep-CAM) is known to express in most epithelial malignancies and was reported as a tumor marker or a candidate of molecular targeting therapy. Ep-CAM cross signaling with N-cadherin involves Pi3K, resulting in the abrogation of the cadherin adhesion complexes in epithelial cells was reported. And Epithelial cell adhesion molecule (Ep-CAM) recently received increased attention as a prognostic factor in breast cancer.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202