Murine Cardiotrophin-1 protein

Biorbyt

Murine Cardiotrophin-1 protein

16

HPLC, SDS-PAGE

Research Use Only

>95%

Cardiotrophin1(CT1)is a member of the cytokine family which also includes IL-6, IL-11, leukemia inhibitory factor (LIF),oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). CT-1 is a pleiotropic cytokine which is expressed in various tissuesincluding the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung. In addition, CT-1 which induces cardiac myocytehypertrophy in vitro can bind to and activate the ILST/gp130 receptor. Murine CT1encodes a 203 amino acid (a.a.) residueprotein that lacks a hydrophobic signal peptide. Human and murine CT1share 80 % a.a. sequence identity and exhibit crossspeciesactivity.

E.coli

2°C to 8°C,-20°C

12352202