Murine IL-36RA protein
ORB107771
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameMurine IL-36RA protein
- Delivery Days Customer16
- Applications SupplierHPLC, SDS-PAGE
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionInterleukin-36 receptor antagonist (IL-36RA) is a secreted protein which belongs to the interleukin 1 cytokine family (IL-1family) and it is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes.IL-36RA hasbeen reported to antagonize the biological activity of IL-36alpha (IL-1F6), IL-36beta (IL-1F8), and IL-36gamma (IL-1F9). Furthermore, itcould constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonistand interleukin-1 receptor type I (IL-1R1). In addition, The receptor for IL-36RA has not been positively identified. Indirectevidence suggests it is IL-1Rrp2. Recombinant murine interleukin-36 RA contains 154 amino acid residues and it shares 91 %a.a. sequence identity with human IL-36RA.
- SourceE.coli
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202