NSC 228155 [113104-25-9]

MedChem Express

NSC 228155 [113104-25-9]

10

113104-25-9

98%

C11H6N4O4S

290.25

NSC 228155 is an activator of EGFR, binds to the extracellular region of EGFR and enhance tyrosine phosphorylation of EGFR. NSC 228155 is also a potent inhibitor of KIX-KID interaction, inhibits kinase-inducible domain (KID) from CREB and KID-interacting domain (KIX) from CBP, with an IC50 of 0.36 microM.

[O-][N+]1=CC=CC=C1SC2=CC=C([N+]([O-])=O)C3=NON=C32

2°C to 8°C,-20°C,-80°C

12352200