OX40 (human):Fc (human) (rec.)

Catalog number: AG-40B-0014-C050
Brand: AdipoGen Life Sciences
Packing: 50 ug
Other sizes: 3 x 50 ug
Price: € 180.00
Expected delivery time: 7 days

Product specifications for - OX40 (human):Fc (human) (rec.)

Product group: Proteins / Signaling Molecule
Category: Proteins
Subcategory: Recombinant protein
Source: HEK 293 cells
Purity: >95% (SDS-PAGE)
Molecular weight: 70 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 1mg/ml after reconstitution.
Form supplied: Lyophilized. Contains PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
Swiss prot ID: P43489
Safety information: 
Additional information: 
Synonyms: AG-40B-0014-C050; AdipoGen Life Sciences; TNFRSF 4; Tumor Necrosis Factor Receptor Superfamily Member 4; CD134