OX40L (mouse) (multimeric) (rec.)

Catalog number: AG-40B-0029-C010
Brand: AdipoGen Life Sciences
Packing: 10 ug
Price: € 180.00
Expected delivery time: 7 days
Quantity:

Product specifications for - OX40L (mouse) (multimeric) (rec.)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Species: Human, Mouse
Target: Tnfsf4
Target description: tumor necrosis factor (ligand) superfamily, member 4
Source: 293 Cells
Properties: 
Purity: >90% (SDS-PAGE)
Molecular weight: ~40kDa (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 0.1 mg/ml
Form supplied: Lyophilized. Contains PBS.
Storage instructions: -20-¦C
Scientific information: 
Scientific info: OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MultimericOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation. - Protein. The extracellular domain of mouse OX40L (aa 52-199) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human and mouse OX40 [CD134]. Purity: >90% (SDS-PAGE). OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MultimericOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation.
Gene ID: 22164
Swiss prot ID: P43488
Safety information: 
MSDS: MSDS
Additional information: 
Synonyms: Ath1; Ath-1; atherosclerosis 1; CD134L; gp34; OX40 ligand; Ox40l; OX-40L; tax-transcriptionally activated glycoprotein 1 ligand; Tnlg2b; tumor necrosis factor ligand 2b; tumor necrosis factor ligand superfamily member 4; TXGP1; Txgp1l
Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA: J. Mestas, et al.; Int. Immun. 17, 737 (2005) Read more