OX40L (mouse) (multimeric) (rec.)

Product specifications for - OX40L (mouse) (multimeric) (rec.)

Overview:
Product group:	Proteins / Signaling Molecule
Category:	Chemokines / cytokines
Source:	HEK 293 cells

Properties:
Purity:	>90% (SDS-PAGE)
Molecular weight:	40 kDa
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352202
Concentration:	0.1mg/ml after reconstitution.
Form supplied:	Lyophilized. Contains PBS.
Storage instructions:	Store at -20°C

Scientific information:
Scientific info:	OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MultimericOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation.
Swiss prot ID:	P43488

Scientific information:

Scientific info:

OX40L is a membrane-expressed cytokine that belongs to the TNF ligand family. It acts as costimulator through interaction with its ligand OX40 on T cells, stimulating T cell activation, proliferation and cytokine production. OX40L is expressed on antigen presenting cells including B cells, dendritic cells, mast cells and endothelium. MultimericOX40L is a high activity construct in which two trimeric OX40L ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively activates T cell proliferation.

Swiss prot ID:

P43488

Safety information:
MSDS:	MSDS

Additional information:
Synonyms:	AG-40B-0029-C010; AdipoGen Life Sciences; ACRP30headless:OX40L; ACRP30headless:CD252; ACRP30headless:CD134L

Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA: J. Mestas, et al.; Int. Immun. 17, 737 (2005)

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Product specifications for - OX40L (mouse) (multimeric) (rec.)