Brepocitinib P-Tosylate [2140301-96-6]

MedChem Express

Brepocitinib P-Tosylate [2140301-96-6]

10

2140301-96-6

Research Use Only

99.69%

C25H29F2N7O4S

561.6

Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 microM, respectively.

O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O

2°C to 8°C,-20°C,-80°C

12352200