Rat IL-22 protein

Biorbyt

Rat IL-22 protein

16

HPLC, SDS-PAGE

Research Use Only

>97%

IL-22 is belonging to IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Membersof this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Producedby T lymphocytes and dendritic cells, IL-10 contributes to the inflammatory response in vivo. IL-22 signals through CRF2-4 andIL-22. It along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays arole in the coordinated response of both adaptive and innate immune systems. Recombinant rat Interleukin-22 contains 146amino acids and it has approximately 79 % and 92 % amino acid sequence identity with human and murine IL-22.

E.coli

2°C to 8°C,-20°C

12352202