Rat MIP-1 beta protein

Biorbyt

Rat MIP-1 beta protein

16

HPLC, SDS-PAGE

Research Use Only

>95%

Recombinant Rat Macrophage Inflammatory Protein-1 beta/CCL4. Chemokine (C-C motif) ligand 4 encoded by the CCL4 gene, also known as macrophage inflammatory protein-1beta (MIP-1beta) is a CC chemokine with specificity for CCR5 receptors and it is a major HIV-suppressive factor produced by CD8+ T cells. In addition, it is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. Recombinant CCL4 induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Furthermore, recombinant rat CCL4 contains 69 amino acids and it shares 80 % and 86 % a.a. sequence identity with human and murine CCL4. Both human and murine MIP-1alpha and MIP-1beta are active on human and murine hematopoietic cells.

E.coli

2°C to 8°C,-20°C

12352202