Sivelestat sodium tetrahydrate [201677-61-4]

MedChem Express

Sivelestat sodium tetrahydrate [201677-61-4]

10

201677-61-4

Research Use Only

99.06%

C20H29N2NaO11S

528.51

Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

CC(C)(C)C(OC1=CC=C(S(=O)(NC2=CC=CC=C2C(NCC(O[Na])=O)=O)=O)C=C1)=O.O.O.O.O

2°C to 8°C,-20°C,-80°C

12352200