STIM1 blocking peptide
GTX31757-PEP
Overview
- SupplierGeneTex
- Product NameSTIM1 blocking peptide
- Delivery Days Customer10
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- Concentration200 ug/ml
- Scientific DescriptionThis gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3 end of this gene situated 1.6 kb from the 5 end of the RRM1 gene.[provided by RefSeq, Jan 2009]
- Storage Instruction-20°C
- UNSPSC12352202