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STIM1 blocking peptide

Research Use Only
GTX31757-PEP
GeneTex
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    STIM1 blocking peptide
  • Delivery Days Customer
    10
  • Applications
    Neutralisation/Blocking
  • Certification
    Research Use Only
  • Concentration
    200 ug/ml
  • Scientific Description
    This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3 end of this gene situated 1.6 kb from the 5 end of the RRM1 gene.[provided by RefSeq, Jan 2009]
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202