TNF-alpha (human) (multimeric) (rec.)

Catalog number: AG-40B-0019-C010
Brand: AdipoGen Life Sciences
Packing: 10 ug
Other sizes: 3 x 10 ug
Price: € 180.00
Expected delivery time: 7 days

Product specifications for - TNF-alpha (human) (multimeric) (rec.)

Product group: Proteins / Signaling Molecule
Category: Chemokines / cytokines
Source: HEK 293 cells
Purity: >95% (SDS-PAGE)
Molecular weight: 34 kDa
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 0.1mg/ml after reconstitution.
Form supplied: Lyophilized. Contains PBS.
Storage instructions: Store at -20°C
Scientific information: 
Scientific info: Tumor necrosis factor (TNF, cachexin or cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. MultimericTNF-alpha is a high activity construct in which two trimeric TNF-alpha ligands are artificially linked via the collagen domain of ACRP30. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (TNF-alpha (human) (multimeric) (rec.) (Prod. No. AG-40B-0019). Since the MultimericTNF-alpha mimics the membrane-bound form (forms oligomers higher than trimer), it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation, either ""normal"" TNF-alpha or MultimericTNF-alpha can be used.
Swiss prot ID: P01375
Safety information: 
Additional information: 
Synonyms: AG-40B-0019-C010; AdipoGen Life Sciences; ACRP30headless:TNF-alpha; ACRP30headless:TNFSF2; ACRP30headless:Tumor Necrosis Factor-alpha