SignalChem is a biotechnology company focused on the research, development and production of innovative cell signaling products. They focus on producing highly purified biologically-active human recombinant proteins. SignalChem strives to support life scientists in academia and biotech by creating effective research tools to advance basic life sciences research and drug discovery efforts.

SignalChem has been devoting resources in creating and developing new research tools related to SARS-CoV-2 virus since the outbreak; they have already established expression systems for production of SARS-CoV-2 Spike proteins, RBD fragments, N protein, and other related protein products on a large scale to help detect IgG / IgM in potential patients.
See their special COVID page.

Bio-Connect supplies all SignalChem products in the Benelux. If you have any questions, please contact the helpdesk.

The SignalChem advantage

  • All-in-one facility
  • High activity
  • Extensive process capabilities
  • Devoid of activation mutations
  • In vivo characteristics
  • Distinguished industry partners and alliances
  • Extensive global customer outreach

Protein products

  • Active enzymes - kinases, phosphatases, phosphodiesterases (PDEs), ubiquitin enzymes, epigenetic enzymes, proteases, GTPases and ATPases.
  • Proteins - adaptor proteins, transcription proteins, enzyme substrates, Tau and phospho-Tau.
  • Reagents - mostly assay reagents (buffer, substrates and co-factors)

Top products

Cat. No.DescriptionAmount
C19S1-8772019 nCoV Human IgG ELISA Kit96 reactions
C19SD-8762019 nCoV S1 Protein ELISA Kit96 reactions
C19NP-G242H2019-nCoV Nucleocapsid (N) Protein10, 20, 50 or 100 ug
C19SD-G241F2019-nCoV Spike protein RBD, Fc Tag10, 20, 50 or 100 ug
C19SD-G241H2019-nCoV Spike protein RBD, HIS Tag10, 20, 50 or 100 ug
C19S1-G241F2019-nCoV Spike protein S110, 20, 50 or 100 ug
2019-nCoV Spike RBD-N Protein Chimera
10, 20, 50 or 100 ug
A51C2-G342FACE2 (18-615) Protein10, 20, 50 or 100 ug
A51C2-G341FACE2 (19-740) Protein10, 20, 50 or 100 ug
A16-10GAKT1, Active5 or 10 ug
P47-10HAMPK (A1/B1/G1), Active5 or 10 ug
C19NP-60HAnti-2019-nCoV N-Protein20 or 100 ug
C19S1-60DHAnti-2019-nCoV Spike Protein, HRP conjugated20 or 100 ug
B10-10HBTK, Active5 or 10 ug
M25-11GGLK, Active5 or 10 ug
G09-10GGSK3 beta, Active5 or 10 ug
M23-11GHPK1, Active5 or 10 ug
N02092-bNTBIO COVID-19 igG/igM Antibody Rapid Test1 ea
R07-10GRIPK1, Active5 or 10 ug
R09-10GRIPK3, Active5 or 10 ug

Broad range of product applications

  • Screening
  • Crystallography
  • Western blot
  • Binding studies
  • Custom applications

Expression system offerings

  • Bacteria - E. coli
  • Yeast - S. Cerevisieae, P. Pastoris
  • Insect - Sf9, Sf21, High 5
  • Plant - Tobacco
  • Mammalian - CHO, HEK, COS

SignalChem responds to the COVID-19 pandemic

For more information, please visit: