Viral Applications

Cells transduction represents a powerful tool to genetically modify a wide variety of cell lines and primary cells. OZ Biosciences has created a comprehensive line of transduction reagents dedicated to viral applications. Wether you want to produce, capture and concentrate viruses or increase transductions efficiencies with Magnetofection or chemicals, OZ Biosciences has something to offer!

ViroMag - Viral transduction enhancer

ViroMag is a versatile reagent offering a solution for many viral applications. ViroMag and virus to be transduced are mixed in a one-step procedure; no molecular biology processes or biochemical modifications are required. This reagent demonstrates an exceptionally high efficiency to promote, control and assist viral transductions. ViroMag is applicable to all viral vectors and presents unique properties due to a specific and optimized magnetic nanoparticles formulation.

Cat. No.DescriptionAmount
VM40100ViroMag 100 Magnetic Transduction Reagent100 ul
VM40200ViroMag 200 Magnetic Transduction Reagent200 ul
VM41000ViroMag 1000 Magnetic Transduction Reagent1 ml
KC30500ViroMag Starting Kit1 kit
KC30600ViroMag Triple Starting Kit1 kit

ViroMag R/L - Retrovirus & Lentivirus infection enhancer

ViroMag R/L transduction reagent is a magnetic nanoparticles formulation optimized for Retroviruses and Lentiviruses. Based on the Magnetofection™ technology, this reagent allows concentrating the complete applied dose of Retro/Lentiviral particles onto cells within minutes, inducing a significant improvement of virus infectivity with extremely low vector doses.

Cat. No.DescriptionAmount
KC30700ViroMag R/L Starting Kit1 kit
RL40100ViroMag RL 100 Magnetic Transduction Reagent100 ul
RL40200ViroMag RL 200 Magnetic Transduction Reagent200 ul
RL41000ViroMag RL 1000 Magnetic Transduction Reagent1 ml

AdenoMag - Adenovirus & AAV infection enhancer

AdenoMag is a magnetic nanoparticles based reagent dedicated to enhance Adenovirus and Adeno Associated Virus (AAV) infection. It allows to concentrate rapidly all viral particles onto cells. AdenoMag permits to improve significantly virus infectivity with extremely low vector doses. Due to its specific properties, AdenoMag is ideal to infect non permissive cells. No molecular biology processes or biochemical modifications are required.

Cat. No.DescriptionAmount
AM70100AdenoMag 100 Magnetic Transduction Reagent100 ul
AM70200AdenoMag 200 Magnetic Transduction Reagent200 ul
AM71000AdenoMag 1000 Magnetic Transduction Reagent1 ml
KC30900AdenoMag Starting Kit1 kit

LentiBlast - Biochemical lentiviral transduction enhancer

LentiBlast is ideal to enhance lentiviral infection and transduction in any type of cells, adherent or in suspension, primary or cell lines. Its patent-protected chemical composition allows simultaneously neutralizing electrostatic repulsions between membrane and viral particles and enhancing viral fusion with cell membrane. Due to a favorable “membrane permeable effect” limiting the transmem-brane potential changes, LentiBlast is totally compatible with cell viability. It overcomes obstacles that prevent successful transduction (cell density, passage number, lentivirus purity, MOI ...).

Cat. No.DescriptionAmount
LB00500Lentiblast Transfection Reagent2 x 500 ul
LB01500Lentiblast Transfection Reagent2 x 1500 ul

AdenoBlast - Biochemical adenoviral transduction enhancer

AdenoBlast is ideal to enhance adenoviral infection in any type of cells, adherent or in suspension, primary or cell lines. The use of adenoviral transduction requires the Coxsackie Adenovirus Receptor (CAR) for its initiation. Many cells express only low amounts of CAR making limited adenovirus-mediated transduction. AdenoBlast is based on an adenovirus binding peptide that assists transduction by coupling the adenoviral particles to the cell membrane in a CAR independent manner.

Cat. No.DescriptionAmount
AB00125AdenoBlast Transfection Reagent125 ul
AB03125AdenoBlast Transfection Reagent3 x 125 ul

Viro-MICSTTM - Efficient and specific target cells transduction

i-MICST™ technology (integrated Magnetic Immuno-Cell Sorting and Transfection/Transduction) is a new platform that allows to genetically modify cells directly on magnetic cell purification columns. This technology combines cell isolation and genetic modification in one simple, efficient and reliable integrated system. Designed for i-MICST™ technology, the Viro-MICST™ reagent allows efficient and specific transduction of target cells directly on magnetic cell-purification columns. Ideal for sensitive cell types such as primary and Stem Cells, Viro-MICST™ leads to an increase in the transduction efficiency with low-titer virus preparations compared to regular transduction methods.

Cat. No.DescriptionAmount
VMX250Viro-MICST 250 Transduction Reagent250 ul
VMX500Viro-MICST 500 Transduction Reagent500 ul
VMX1000Viro-MICST 1000 Transduction Reagent1 ml

Mag4C - Magnetic Virus Concentration

Mag4C Kit is specifically designed and developed for capturing, concentrating and storing viruses. This kit is composed of three reagents allowing Magnetic Capture/Concentration, Elution and Conservation of viruses. Mag4C magnetic nanoparticles capture viruses in culture media with 80-99% efficiency. Once captured onto magnetic beads, viruses can be:
• Concentrated and stored with the conservation buffer or directly used for downstream assays
• Concentrated, eluted from the magnetic beads with the elution buffer and stored with the conservation buffer or used for various assays

Cat. No.DescriptionAmount
AKC11000Mag4C AD Kit1 kit
ATK11200Mag4C AD Trial Kit1 kit
LKC11000Mag4C LV Kit1 kit
LTK11200Mag4C LV Trial Kit1 kit

Calcium Phosphate Transfection Kit - Virus Production

Calcium Phosphate transfection Kit is perfect to transfect HEK-293 cells. This transfection method, first described by Graham and Van Der Ebb in 1973, has been optimized in order to reach higher transfection efficiency. The CaPO transfection Kit is simple and easy to use. It allows reaching between 95 and 100% of HEK 293 transfected cells and a very high titer for virus production.

Cat. No.DescriptionAmount
CP90000CaPo Transfection Kit1 kit