Overview
- SupplierGeneTex
- Product NameADAR2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Shoshan E et al., 2015 Mar, Nat Cell BiolRead more
- Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers. Wang Y et al., 2017 Jul, Genome ResRead more
- Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing. Freund EC et al., 2020 May 19, Cell RepRead more