AGER antibody, PAb

Biorbyt

AGER antibody, PAb

10

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen

Western blot - 0.1-0.5 μg/ml Immunohistochemistry(Paraffin-embedded Section) - 0.5-1 μg/ml Immunohistochemistry(Frozen Section) - 0.5-1 μg/ml IHC-Fr, WB, IHC

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to AGER. The receptor for advanced glycation end products (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimers disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in several inflammatory disorders and diabetes, and it also functions as an endothelial adhesion receptor promoting leukocyte recruitment.

Hamster, Human, Mouse, Rat

2°C to 8°C,-20°C

12352203