Aha1 Antibody (OASE00144)

Aviva Systems Biology

Aha1 Antibody (OASE00144)

23

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Monoclonal

4H9-D7

1 mg/ml

Unconjugated

AHSA1

activator of HSP90 ATPase activity 1

activator of 90 kDa heat shock protein ATPase homolog 1; AHA1; AHA1, activator of heat shock 90kDa protein ATPase homolog 1; C14orf3; hAha1; p38

Mouse

IgG1

Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4).

Human, Mouse

-20°C

12352203