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ProductsBack/AHR antibody [RPT1]
GTX22770 IHC-P Image
GTX22770 IHC-P Image
GTX22770 IHC-P Image

AHR antibody [RPT1]

Research Use Only
GTX22770
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Porcine, Primate, Rat
Price on request
Packing Size
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    GeneTex
  • Product Name
    AHR antibody [RPT1]
  • Delivery Days Customer
    10
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    RPT1
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]
  • Reactivity
    Human, Mouse, Porcine, Primate, Rat
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Aryl hydrocarbon receptor-ligand axis mediates pulmonary fibroblast migration and differentiation through increased arachidonic acid metabolism. Su HH et al., 2016 Aug 31, Toxicology
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  • Exposing human primary dermal fibroblasts to particulate matter induces changes associated with skin aging. Reynolds WJ et al., 2020 Nov, FASEB J
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  • Functional expression of aryl hydrocarbon receptor on mast cells populating human endometriotic tissues. Mariuzzi L et al., 2016 Sep, Lab Invest
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  • IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression. Sadik A et al., 2020 Sep 3, Cell
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  • Severe liver cirrhosis markedly reduces AhR-mediated induction of cytochrome P450 in rats by decreasing the transcription of target genes. Floreani M et al., 2013, PLoS One
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