GTX103219 IHC-P Image
alpha Actinin 2 antibody [N1N3]
GTX103219
Product group Antibodies
Overview
- SupplierGeneTex
- Product Namealpha Actinin 2 antibody [N1N3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.67 mg/ml
- IsotypeIgG
- Scientific DescriptionAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- PFN2a Suppresses C2C12 Myogenic Development by Inhibiting Proliferation and Promoting Apoptosis via the p53 Pathway. Li H et al., 2019 Aug 23, CellsRead more
- ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart. Jin JK et al., 2017 Mar 3, Circ ResRead more
- Cardiac Depression in Pigs after Multiple Trauma - Characterization of Posttraumatic Structural and Functional Alterations. Kalbitz M et al., 2017 Dec 19, Sci RepRead more
- Early myocardial damage (EMD) and valvular dysfunction after femur fracture in pigs. Weber B et al., 2021 Apr 19, Sci RepRead more
- Masticatory Functional Load Increases the mRNA Expression Levels of ACTN2 and ACTN3 and the Protein Expression of alpha-Actinin-2 in Rat Masseter Muscle. Masita Silviana N et al., 2021 Feb 25, Turk J Pharm SciRead more
- Qishen Yiqi Dropping Pills Ameliorates Doxorubicin-induced Cardiotoxicity in Mice via Enhancement of Cardiac Angiogenesis. Wang L et al., 2019 Apr 3, Med Sci MonitRead more
- Regulation of cardiomyocyte DNA damage and cell death by the type 2A protein phosphatase regulatory protein alpha4. Cowan J et al., 2021 Mar 18, Sci RepRead more
- Sensory contact to the stressor prevents recovery from structural and functional heart damage following psychosocial trauma. Foertsch S et al., 2019 Aug, Brain Behav ImmunRead more
- Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training. Roberts MD et al., 2018, PeerJRead more
- The effects of artocarpin on wound healing: in vitro and in vivo studies. Yeh CJ et al., 2017 Nov 15, Sci RepRead more