anti-alpha Synuclein phospho (Tyr136) antibody
ARG51766
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetSNCA
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-alpha Synuclein phospho (Tyr136) antibody
- Delivery Days Customer23
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6622
- Target nameSNCA
- Target descriptionsynuclein alpha
- Target synonymsalpha-synuclein; I+/--synuclein; NACP; non A-beta component of AD amyloid; PARK1; PARK4; PD1; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); truncated alpha synuclein
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionMay be involved in the regulation of dopamine release and transport. Soluble protein, normally localized primarily at the presynaptic region of axons, which can form filamentous aggregates that are the major non amyloid component of intracellular inclusions in several neurodegenerative diseases (synucleinopathies). Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203