anti-APC5 antibody
ARG55134
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetANAPC5
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-APC5 antibody
- Delivery Days Customer23
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID51433
- Target nameANAPC5
- Target descriptionanaphase promoting complex subunit 5
- Target synonymsanaphase-promoting complex subunit 5; APC5; cyclosome subunit 5
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203