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anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (Biotin)

Research Use Only
ANC-273-030
Ancell Corporation
ApplicationsFlow Cytometry, ELISA, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
Price on request
Packing Size
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Overview

  • Supplier
    Ancell Corporation
  • Product Name
    anti-CD273 [B7-DC/PD-L2] (human), mAb (ANC8D12) (Biotin)
  • Delivery Days Customer
    10
  • Applications
    Flow Cytometry, ELISA, Neutralisation/Blocking
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    ANC8D12
  • Conjugate
    Biotin
  • Estimated Purity
    >95%
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation. - Monoclonal Antibody. Isotype: Mouse IgG2akappa. Clone: ANC8D12. Applications: ELISA, FACS, FUNC (Blocking). 50mM Sodium Phosphate pH 7.5, 100mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2% BSA, 0.04% NaN3 (as a preservative). CD273 (B7-DC; PD-L2) is a type I surface molecule with homology to CD80, CD86, CD274. It is expressed primarily by dendritic cells and provides a stimulatory signal to CD279 (PD-1; Programmed Cell Death 1) which has an important immunoregulatory role by downregulating the T cell response. CD273 binds to CD279 (PD-1) with a 2-6 fold higher affinity than CD274 and is an important component of immune regulation.
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203