anti-CD41 antibody [MWReg30]

Arigo Biolaboratories

anti-CD41 antibody [MWReg30]

23

Functional Assay, Flow Cytometry, ImmunoPrecipitation, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Monoclonal

MWReg30

1 mg/ml

Unconjugated

>95%

Itga2b

integrin alpha 2b

AI172977; al; alpha IIb; alphaIIb; CD41; CD41B; Gp; GP IIb; GPalpha IIb; GpIIb; integrin alpha-IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet membrane glycoprotein IIb

Rat

IgG1

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

Mouse

-20°C

12352203