anti-CD62L / L-Selectin antibody [DREG56] (FITC)
ARG62907
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetSELL
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD62L / L-Selectin antibody [DREG56] (FITC)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDDREG56
- ConjugateFITC
- Gene ID6402
- Target nameSELL
- Target descriptionselectin L
- Target synonymsCD62 antigen-like family member L; CD62L; gp90-MEL; LAM1; LECAM1; LEU8; leukocyte surface antigen Leu-8; leukocyte-endothelial cell adhesion molecule 1; LNHR; LSEL; L-selectin; LYAM1; lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; TQ1
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1). The level of CD62L expression can be used to help distinguish naive T cells from effector/memory T cells.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203