anti-CD62L / L-Selectin antibody [MEL-14]

Arigo Biolaboratories

anti-CD62L / L-Selectin antibody [MEL-14]

23

Functional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Monoclonal

MEL-14

1 mg/ml

Unconjugated

>95%

Sell

selectin, lymphocyte

AI528707; CD62; CD62 antigen-like family member L; CD62L; L; LAM-1; LECAM; LECAM1; LECAM-1; leukocyte adhesion molecule 1; leukocyte-endothelial cell adhesion molecule 1; Lnhr; L-sel; L-selectin; Ly-2; Ly-22; Lya; Lyam; Lyam1; Lyam-1; Ly-m2; Ly-m22; lymph node homing receptor; lymphocyte antigen 22; lymphocyte surface MEL-14 antigen

Rat

IgG2a

CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).

Mouse

-20°C

12352203