anti-CD62P / P-Selectin antibody [AK4] (PE)
ARG54216
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman
TargetSELP
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD62P / P-Selectin antibody [AK4] (PE)
- Delivery Days Customer23
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAK4
- ConjugateRPE
- Gene ID6403
- Target nameSELP
- Target descriptionselectin P
- Target synonymsCD62; CD62 antigen-like family member P; CD62P; GMP140; GMP-140; granule membrane protein 140; granule membrane protein 140kDa; granulocyte membrane protein; GRMP; LECAM3; leukocyte-endothelial cell adhesion molecule 3; PADGEM; platelet activation dependent granule-external membrane protein; platelet alpha-granule membrane protein; PSEL; P-selectin; selectin P (granule membrane protein 140kDa, antigen CD62)
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling, probably by increasing rebinding within a bond cluster.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203