anti-CD80 antibody [MEM-233]
ARG62931
ApplicationsFlow Cytometry, ImmunoPrecipitation
Product group Antibodies
ReactivityHuman
TargetCD80
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD80 antibody [MEM-233]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, ImmunoPrecipitation
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMEM-233
- Concentration1 mg/ml
- ConjugateUnconjugated
- Estimated Purity>95%
- Gene ID941
- Target nameCD80
- Target descriptionCD80 molecule
- Target synonymsactivation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; LAB7; T-lymphocyte activation antigen CD80
- HostMouse
- IsotypeIgG1
- Scientific DescriptionCD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203