anti-CHEK1 antibody
ARG54733
ApplicationsWestern Blot
Product group Antibodies
TargetCHEK1
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CHEK1 antibody
- Delivery Days Customer23
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2G1D5
- ConjugateUnconjugated
- Gene ID1111
- Target nameCHEK1
- Target descriptioncheckpoint kinase 1
- Target synonymscell cycle checkpoint kinase; Checkpoint, S. pombe, homolog of, 1; CHK1; CHK1 checkpoint homolog; Chk1-S; serine/threonine-protein kinase Chk1
- HostMouse
- Scientific DescriptionThe protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011]
- Storage Instruction-20°C
- UNSPSC12352203