anti-CrkII antibody

Arigo Biolaboratories

anti-CrkII antibody

23

Western Blot

Research Use Only

Monoclonal

1 mg/ml

Unconjugated

CRK

CRK proto-oncogene, adaptor protein

adapter molecule crk; CRKII; p38; proto-oncogene c-Crk; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene-like protein

Mouse

IgG2b

The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.

Human

-20°C

12352203