anti-HDAC3 antibody

Arigo Biolaboratories

anti-HDAC3 antibody

23

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry

Research Use Only

Polyclonal

Unconjugated

HDAC3

histone deacetylase 3

HD3; histone deacetylase 3; KDAC3; RPD3; RPD3-2; SMAP45

Rabbit

IgG

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203