anti-Helios antibody [22F6] (PE)

Arigo Biolaboratories

anti-Helios antibody [22F6] (PE)

23

Flow Cytometry

Research Use Only

Monoclonal

22F6

RPE

IKZF2

IKAROS family zinc finger 2

ANF1A2; HELIOS; ikaros family zinc finger protein 2; zinc finger DNA binding protein Helios; zinc finger protein Helios; zinc finger protein, subfamily 1A, 2 (Helios); ZNF1A2; ZNFN1A2

Hamster

IgG

Helios, also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios, Aiolos and Ikaros is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells, Helios has been strongly associated with Treg cells.

2°C to 8°C

12352203