anti-IL1 beta antibody

Arigo Biolaboratories

anti-IL1 beta antibody

23

Functional Assay, Western Blot, ELISA

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Il1b

interleukin 1 beta

IL-1 beta; IL-1F2; interleukin-1 beta

Rabbit

IgG

IL1 beta protein is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]

Rat

-20°C

12352203