anti-IL13 antibody [JES10-5A2] (low endotoxin)

Arigo Biolaboratories

anti-IL13 antibody [JES10-5A2] (low endotoxin)

23

Flow Cytometry, ImmunoFluorescence, ELISA, ELISpot Assay, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking

Research Use Only

Monoclonal

JES10-5A2

0.5 mg/ml

Unconjugated

IL13

interleukin 13

IL-13; interleukin-13; P600

Rat

IgG1

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]

Human

-20°C

12352203