anti-Sirtuin 2 (human), mAb (S2R233-1)

AdipoGen Life Sciences

anti-Sirtuin 2 (human), mAb (S2R233-1)

10

Western Blot, ELISA

Research Use Only

Monoclonal

S2R233-1

1 mg/ml

SIRT2

sirtuin 2

NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; regulatory protein SIR2 homolog 2; silent information regulator 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; sirtuin type 2

Mouse

IgG2b

Monoclonal Antibody. Recognizes human sirtuin 2. Detects a band of ~45kDa by Western blot. Isotype: Mouse IgG2bkappa. Clone: S2R233-1. Applications: ELISA, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the Lys-40 of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimers disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntingtons and Parkinsons disease. - Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the Lys-40 of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimers disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntingtons and Parkinsons disease.

Human

2°C to 8°C,-20°C

12352203