anti-TBL1X / TBL1XR1 antibody

Arigo Biolaboratories

anti-TBL1X / TBL1XR1 antibody

23

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

TBL1X

transducin beta like 1 X-linked

CHNG8; EBI; F-box-like/WD repeat-containing protein TBL1X; SMAP55; TBL1; transducin beta like 1X-linked; transducin beta-like protein 1X; transducin-beta-like protein 1, X-linked

Goat

IgG

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene. [provided by RefSeq, Nov 2008]

Bovine, Canine, Human, Mouse, Rat

-20°C

12352203