GTX119872 ICC/IF Image
GTX119872 ICC/IF Image
ARS2 antibody
GTX119872
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameARS2 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.76 mg/ml
- IsotypeIgG
- Scientific DescriptionActs as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages. Yin J et al., 2020 Jun 12, Nat CommunRead more
- Global Identification of Human Exosome Substrates Using RNA Interference and RNA Sequencing. Lloret-Llinares M et al., 2020, Methods Mol BiolRead more