GTX112387 ICC/IF Image
GTX112387 ICC/IF Image
ATP citrate lyase antibody [N1N2], N-term
GTX112387
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameATP citrate lyase antibody [N1N2], N-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.55 mg/ml
- IsotypeIgG
- Scientific DescriptionATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed Rats. Garcia-Arroyo FE et al., 2019 Oct 11, BiomoleculesRead more
- Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Li X et al., 2017 Jun 1, Mol CellRead more