Aurora B Antibody / AURKB

Biorbyt

Aurora B Antibody / AURKB

16

IHC (FFPE): 1-2ug/ml for 30 min at RT IHC-P

Research Use Only

ARRK2-1

IgG

Aurora B is a serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. [UniProt]

12352203