Basic Cytokeratin Antibody

Biorbyt

Basic Cytokeratin Antibody

16

ImmunoHistoChemistry

Immunohistochemistry (FFPE): 0.25-0.5ug/ml for 30 min at RT IHC-P

Research Use Only

KRTH/1576R

IgG

This mAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50 , 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

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