Bcl-XL antibody [4A9] - Overexpression Validated

GeneTex

Bcl-XL antibody [4A9] - Overexpression Validated

10

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

4A9

0.25 mg/ml

Mouse

IgG

Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Isoform Bcl-X(S) promotes apoptosis.

Human, Mouse

2°C to 8°C,-20°C

12352203