c8orf84 antibody

Biorbyt

c8orf84 antibody

16

ELISA

ELISA: 1:500-1000, IHC-P: 1:100-500, ICC: 1:100-500, IF: 1:100-500 ELISA, ICC, IF, IHC-P

Research Use Only

1 mg/ml

IgG

RPE-spondin (RPESP) is a 264 amino acid protein encoded by a gene mapping to human chromosome 8. Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

-20°C

12352203