GTX22860 IHC-P Image
Calmodulin antibody [2D1]
GTX22860
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
Product group Antibodies
ReactivityBacteria, Bovine, Chicken, Fungus, Human, Mammals, Mouse, Rat, Other Species
Overview
- SupplierGeneTex
- Product NameCalmodulin antibody [2D1]
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2D1
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionCalmodulin is a small, highly conserved calcium binding protein found in all eukaryotic cells. With the capacity to bind up to four calcium ions, this 17 kDa protein acts as an important intracellular receptor for regulatory calcium signals. As it binds calcium, calmodulin undergoes conformational changes which can increase its affinity for target proteins. It acts both directly, through interaction with key target enzymes, and indirectly, via specific kinases. Studies have found that calmodulin participates in the regulation of several biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of both cAMP and calcium concentrations.
- ReactivityBacteria, Bovine, Chicken, Fungus, Human, Mammals, Mouse, Rat, Other Species
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Comparative proteomics analysis of vascular smooth muscle cells incubated with S- and R-enantiomers of atenolol using iTRAQ-coupled two-dimensional LC-MS/MS. Sui J et al., 2008 Jun, Mol Cell ProteomicsRead more