CARM1 antibody, PAb

Biorbyt

CARM1 antibody, PAb

10

Western Blot

Western blot - 0.1-0.5 μg/ml - Human, Rat - Mouse - WB

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

CARM1 (coactivator-associated arginine methyltransferase 1), also known as PRMT4, is an enzyme encoded by the CARM1 gene found in human beings, as well as many other mammals. This gene is mapped to 19p13.2. CARM1 is a regulator of cyclin E1 and DHFR mRNA expression. Its main function includes catalyzing the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. CARM1 is a secondary coactivator through its association with p160 family (SRC-1, GRIP1, AIB) of coactivators. It is responsible for moving cells toward the inner cell mass in developing blastocysts. This gene also plays an important role in androgen receptors and may play a role in prostate cancer progression.

Hamster, Human, Mouse, Rat

2°C to 8°C,-20°C

12352203