CD160 antibody

Catalog number: GTX17209_100ug
Brand: GeneTex
Packing: 100 ug
Price: € 463.00
Expected delivery time: 10 days
Quantity:
GTX17209 ICC/IF Image
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GTX17209 WB Image
GTX17209 ICC/IF Image...

Product specifications for - CD160 antibody

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Application: ELISA; ImmunoCytoChemistry; ImmunoFluorescence; Western Blot
Species: Human, Mouse
Host: Rabbit
Target: CD160
Target description: CD160 molecule
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Controle: K562 Cell Lysate(GTX27911)
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 1 mg/ml
Storage instructions: 2-¦C to 8-¦C, -20-¦C or -80-¦C
Scientific information: 
Scientific info: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MH
Gene ID: 11126
Swiss prot ID: O95971
Additional information: 
Synonyms: BY55; CD160 antigen; CD160 transmembrane isoform; CD160-delta Ig; natural killer cell receptor BY55; natural killer cell receptor, immunoglobulin superfamily member; NK1; NK28