CD261 antibody, MAb
ORB154420
ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
Overview
- SupplierBiorbyt
- Product NameCD261 antibody, MAb
- Delivery Days Customer10
- ApplicationsFunctional Assay, Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry
- Applications SupplierFACS, ICC, IF, IP, FA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDDR-4-02
- Concentration1 mg/ml
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMouse monoclonal antibody to CD261 which is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to activated CD261 which is expressed in most human tissues including spleen, peripheral blood leucocytes, thymus and in a variety oFT tumour-derived cell lines. It plays a role in inducing cell death. The binding oFT TRAIL to DR4 triggers the activation oFT pro-caspases 8 and 10, leading to apoptosis.
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203