CD27 antibody [7H21]

GeneTex

CD27 antibody [7H21]

10

Flow Cytometry, Western Blot, Neutralisation/Blocking

Research Use Only

Monoclonal

7H21

500 ug/ml

Mouse

IgG

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C,-20°C

12352203